Ethene derivatives

摘要

Ethene derivatives of the formula: [R5(R1CR4=CR2R3)m]n I wherein R5 represents optionally substituted heterocyclyl or a group -CR4=CR2R3, or optionally substituted aryl, heterocyclylalkyl or arylalkyl and R1 represents -NR6- wherein R6 represents hydrogen or optionally substituted alkyl or aryl, or R5 represents a quinonoidal group, and R1 represents =N-, R4 represents hydrogen, alkoxy, alkylthio, trifluoromethyl or optionally substituted alkyl or aryl, R2 represents cyano, formyl, alkoxycarbonyl, alkylsulphonyl, dialkylcarbamoyl, dialkylthiocarbamoyl, aryloxycarbonyl, arylsulphinyl or arylsulphonyl, R3 represents a group R2 or hydrogen, nitro or optionally substituted aryl or aroyl or alkanoyl, and m and n are 1 or 2, and pharmaceutically acceptable salts thereof, with the exclusion of certain compounds in which R5 represents pyridyl, 5-halogenopyrid-2-yl or 1,2,4-triazolo[4,3-a]-quinoline possess useful pharmacological properties.