| 摘要 |
Dipeptides of formula (I), in which R is methyl, hydroxy-methyl or other gp., R1 is methoxy, cyclohexyl, isopropyl, alkylamino or other gp. and R2 is methylene carboxyl or carboxyl, for use as sweeteners, are made by (a) reacting an amino acid with aryl or substd. alkaryl aceto-acetate to obtain an enamine; (b) reacting this with a 4-12C alkanoyl chloride to obtain a carboxyl-activated alpha-enamine of formula (II); and (c) reacting this with an amino-acid deriv. |
