| 摘要 |
<p>The invention provides novel imidazoquinolines, processes for their preparation and pharmaceutical compositions containing them. The compounds have Formula I <CHEM> wherein A is a C1-C4 straight or branched alkylene chain which may be saturated or unsaturated, B is a C2-C4 straight or branched alkylene chain which may be saturated or unsaturated, R<1> and R<2> are the same or different and are hydrogen, alkyl, alkoxy, alkoxyalkyl, hydroxyalkyl, hydroxy, halogen, nitro, carboxy, carboxylic ester, carbamoyl, carbamoyloxy, cyano, acyl, acylamino or trifluoromethyl, Het is a heterocyclic group chosen from imidazolyl, imidazolinyl, benzimidazolyl, thiazolyl, thiazolinyl, quinolyl, piperidyl, pyridyl, benzothiazolyl and pyrimidyl, any of which heterocyclic groups may be substituted, and x is 0 or 1, and pharmaceutically acceptable salts thereof. The compounds are anti-ulcer/anti-secretory agents.</p> |
