发明名称 TETRAHYDROISOQUINOLINE DERIVATIVES,THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
摘要 Compound of the formula …<CHEM>… wherein R1 and R2 are each independently -H or lower alkoxy; R3 and R4 are each independently lower alkyl; and R5 and R6 are each -OCH3, or together form -OCH2O- or -OCH2CH2O-, and pharmaceutically acceptable acid addition salts thereof are disclosed as calcium channel blockers useful for treating cardiovascular disorders, including angina, hypertension and congestive heart failure.
申请公布号 IL80824(D0) 申请公布日期 1987.03.31
申请号 IL19860080824 申请日期 1986.12.01
申请人 SYNTEX (U.S.A.) INC. 发明人
分类号 C07D319/18;A61K31/47;A61K31/472;A61P9/00;A61P9/10;A61P9/12;A61P43/00;C07C67/00;C07C253/00;C07C255/42;C07C255/43;C07D217/04;C07D217/18;C07D217/20;C07D405/06;C07D405/12 主分类号 C07D319/18
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