发明名称 |
AGENT FOR FILLING IN SOFT CAPSULE |
摘要 |
PURPOSE:The titled uniform and stable agent, obtained by incorporating an aqueous solution of pantethine which is an ameliorant of lipid metabolism and tocopherol acetate which is an ameliorant of peripheral blood stream with a specific glycerol ester of a fatty acid in a specific amount and having good formulating efficiency. CONSTITUTION:An agent for filling in a soft capsule obtained by incorporating (A) a 70-90% aqueous solution of pantethine and (B) tocopherol acetate (hereinafter abbreviated to.E.) with (C) a glycerol ester of a fatty acid with >=40-<60% caprylic acid monoglyceride content as an excipient. The compounding ratio of the respective components is 0.25-1 weight ratio of the components (A) and (B) to the component (C). The use of the component (C) as an excipient provides a clear agent containing the pantethine and V.E. which has not been available in the past. Thereby, the agent can be formulated as one grain soft capsule. |
申请公布号 |
JPS6267020(A) |
申请公布日期 |
1987.03.26 |
申请号 |
JP19850205680 |
申请日期 |
1985.09.18 |
申请人 |
NISSHIN KAGAKU KK |
发明人 |
IIJIMA TAKEO;SHIMIZU SUZUKO |
分类号 |
A61K31/355;A61K9/48;A61K31/16;A61K31/23;A61K31/352;C07D311/72 |
主分类号 |
A61K31/355 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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