发明名称 Use of sulfanilamido quinoxalines in the treatment of neoplastic diseases.
摘要 Compounds of formula II <CHEM> wherein: Y is a substituent attached to any of the unsubstituted carbons on the quinoxaline ring which substituent is selected from NH2, NO2, OCH3, hydroxy, hydrogen, methyl, fluoro, chloro or bromo; Z is hydrogen or halo; and X is selected from -NO2, NH2 acylamide, and groups having the formula: NH-(CH2)n-COOH or NHCH2SO3H wherein n is an integer of 1-6 are used for preparing pharmaceutical compositions for the treatment of neoplastic diseases.
申请公布号 EP0215200(A2) 申请公布日期 1987.03.25
申请号 EP19860108295 申请日期 1986.06.18
申请人 MERCK & CO. INC. 发明人 TOLMAN, RICHARD L.
分类号 C07D241/44;A61K31/495;A61K31/635;A61P35/00 主分类号 C07D241/44
代理机构 代理人
主权项
地址