摘要 |
Compounds of formula II <CHEM> wherein: Y is a substituent attached to any of the unsubstituted carbons on the quinoxaline ring which substituent is selected from NH2, NO2, OCH3, hydroxy, hydrogen, methyl, fluoro, chloro or bromo; Z is hydrogen or halo; and X is selected from -NO2, NH2 acylamide, and groups having the formula: NH-(CH2)n-COOH or NHCH2SO3H wherein n is an integer of 1-6 are used for preparing pharmaceutical compositions for the treatment of neoplastic diseases.
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