发明名称 FUSION PROTEINS,A PROCESS FOR THEIR PREPARATION AND THEIR USE
摘要 1. Claims for the Contracting States : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE A fusion protein of the general formula Met - Xn - D' - Y - Z in which n is zero or 1, X is a sequence of 1 to 12 genetically codable amino acids, D' is a sequence of about 70 amino acids in the region of the sequence of amino acids 23 - 93 of the D-peptide in the trp operon of E. coli, Y denotes a sequence of one or more genetically codable amino acids which permits the following amino acid sequence Z to be cleaved off, and Z is a sequence of genetically codable amino acids. 1. Claims for the Contracting State : AT A process for the preparation of a fusion protein of the general formula (1) Met - Xn - D' - Y - Z in which n is zero or 1, X is a sequence of 1 to 12 genetically codable amino acids, D' is a sequence of about 70 amino acids in the region of the sequence of amino acids 23 - 93 of the D-peptide in the trp operon of E. coli, Y denotes a sequence of one or more genetically codable amino acids which permits the following amino acid sequence Z to be cleaved off, and Z is a sequence of genetically codable amino acids, characterized by expressing a gene structure which codes for these fusion proteins in a host cell, and separating the fusion protein.
申请公布号 ZA8605556(B) 申请公布日期 1987.03.25
申请号 ZA19860005556 申请日期 1986.07.25
申请人 HOECHST AKTIENGESELLSCHAFT 发明人 PAUL HABERMANN;SIEGFRIED STENGELIN;FRIEDRICH WENGENMAYER
分类号 C12N15/09;C07H21/04;C07K1/107;C07K14/00;C07K14/575;C07K14/62;C07K14/81;C07K14/815;C07K19/00;C12N1/20;C12N15/00;C12N15/62;C12P21/00;C12P21/02 主分类号 C12N15/09
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