发明名称 |
Method for the production of acemetacin |
摘要 |
1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid carboxymethyl ester as known per se is obtainable by a novel and more simple method comprising mild acid hydrolysis of 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetoxyacetic tetrahydropyran-2-yl ester. The final product is a valuable drug having antiinflammatory activity.
|
申请公布号 |
US4652659(A) |
申请公布日期 |
1987.03.24 |
申请号 |
US19840661537 |
申请日期 |
1984.10.16 |
申请人 |
SIEGFRIED AKTIENGESELLSCHAFT |
发明人 |
GNEHM, RENE;WEBER, ROLF |
分类号 |
C07D209/28;C07D309/10;(IPC1-7):C07D209/28 |
主分类号 |
C07D209/28 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|