| 摘要 |
Sweetening agents of formula (I) and their tautomers and salts are new: X3-X5=H, Br, CF3, CF2CF3, CH2CF3, 1-4C alkyl, CH=NOMe, CH=NOH, CHO, CH2OMe, CH2OH, Cl, CN, COCF3, 2-4C alkanoyl, CONH2, mono- or di(1-3C alkyl)carbamoyl, 2-4C alkoxycarbonyl, COOH, F, I, NH2, mono- di(1-3C alkyl)amino, NHCHO, NHCOMe, NHCONH2, NHSO2Me, NO2, 1-3C alkoxy, OCOMe, OH, 1-3C alkylthio, 1-3C alkylsulphinyl, 1-3C alkylsulphonyl, SO2NH2, mono- or di(1-3C alkyl)sulphamoyl or SO3H; A=N or C; R1=H or 1-4C hydrocarbyl in which 1 or 2 atoms are opt. replaced by N, O, S, Cl, Br and/or I and 1-3 H atoms are opt. replaced by F; R2=2-13C hydrocarbyl in which 1-4C atoms are opt. replaced by N, O, S, Cl, Br and/or I and 1-5 H atoms are opt. replaced by F; or R1, and R2 may be linked together; R3=H or 1-3C alkyl; R4=H or Me; provided that (a) R1 and R2 are not CN or OMe when X4=CN or NO2 and X3, X5, R3 and R4 are all H, and (b) R1 is not NO2, SOMe or SOEt and R2 is not NO2, SOR, SO2R, SO2NHR or SO2N(R)2 when X4=H, CF3, CHO, Cl, CN, COMe, F or NO2 and X3, X5, R3 and R4 are all H, when R=1-10C alkyl, cycloalkyl or aryl in which 1 or 2 C atoms are opt. replaced by S or O. |
