Dihydrobenzo/b /thiophenes and pharmaceutical compositions thereof useful as antifungals.

摘要

2-Alkyl-, 2-alkenyl- and 2-alkynyl-2,3-dihydro-2-(1H-azo- lyl(C<Sub>1</Sub>-C<Sub>2</Sub>)alkyl)benzo[b]thiophenes especially 2-alkyl-, 2-alkenyl- and 2-alkynyl-2,3-dihydro-3-hydroxy-2-(1H-1-imidazolylmethyl)-4-, 5-, 6- and 7-halobenzo[b]thiophenes and related derivatives having antifungal activity are disclosed. Pharmaceutical compositions comprising compounds of the invention and their use in treating fungal infections in susceptible hosts such as humans are also disclosed.