INTERFERON GEL FORMULATIONS

摘要

A kit for formulating and dispensing an alpha-type interferon gel composition comprising a) a vial having an open end aseptically sealed and containing about 1 x 104 to 5 x 108 International Units of lyophilized alpha-type interferon formulation prepared from an alpha-type interferon having a specific activity of at least 5 x 10 International Units/mg. total protein; and b) a tube having flexible walls and sealing means at its open end and containing a dermatologically acceptable vehicle which contains a compatible preservative and a sufficient amount of polyoxyethylene polyoxypropylene block polymer for the vehicle to be liquid at about 15.degree.C. and below and which together with the lyophilized alpha-type interferon gels at 15.degree.C. and above; and methods for preparing said gel using said kit.