| 摘要 |
<p>A method of effecting biotransformations comprises, as a first step, the fixation of biological material from suspension by passing suspension through a liquid permeable member which is capable of filtering the biological material. The liquid permeable member is an integral body or a composite body whose components are maintained in a substantially fixed relationship to each other. The biological material may comprise living or biochemically active cells and/or tissues and/or particles which themselves comprise pre-immobilised biocatalysts. After fixation, the biochemical transformation is effected by contacting the biological material supported on the member with a liquid and/or gaseous medium to form a product and/or biomass. Finally, the product is recovered and/or the biomass is harvested. Various apparatus for effecting the fixation of the biological material are described and generally incorporate means for establishing a relative velocity between the liquid permeable body and the suspension so as to effect the filtration. Also described are reactor systems comprising biological material which has been entrapped by fixation on a liquid permeable support body. The invention may be applied to the fixation of plant cells for growth into "plantlets" (i.e. micropropagation).</p> |
