摘要 |
<p>Benzodiazepine derivs. of formula (I) in which R, is H or lower alkyl for use as tranquillisers or intermediates, are made by reaction of 7-chloro 1-methyl 5-phenyl 3H-1, 4-benzodiazepin 2(1H)-one with a cpd. of formula (II), in organic solvent in presence of a reactive bromine acceptor, at ambient temp.</p> |