摘要 |
<p>A method for parenteral administration of fat-soluble pharmaceuticals and vitamins using microemulsions. The microemulsions are comprised of a naturally occurring amphipatic substance and a hydrophobic lipid along with the active ingredient, are size selected for 1,000 ↓∃ 300 A^o pseudomicelles, and permit safe intravenous injection of the active ingredient. Levels of the active ingredient in the various lipoprotein fractions of serum appear to mimic the natural distribution of the administered drug if taken orally.</p> |