发明名称 Antihypertensive agents.
摘要 The invention describes antihypertensive agents of formula <CHEM> in which R<1> is a phenyl group substituted by defined substituents, R<2> is C1-C6 alkyl, R<3> is a group of formula <CHEM> where R<7> is independently hydrogen or defined substituents, R<8> is hydrogen, C1-C6 alkyl or C1-C6 alkoxy, R<9>, R<1><0> and R<1><1> are independently hydrogen or C1-C6 alkyl, n is 0,1,2,3 or 4; s is 1,2,3,4 or 5; p is 0 or 1 providing that when R<8> is C1-C6 alkoxy p is 0, or R<3> is <CHEM> where m is 1,2,3 or 4 or a pharmaceutically acceptable salt thereof. Also described are processes for preparing the compounds, intermediates used in such processes and pharmaceutical compositions containing the active compounds.
申请公布号 EP0211584(A1) 申请公布日期 1987.02.25
申请号 EP19860305734 申请日期 1986.07.25
申请人 AMERICAN HOME PRODUCTS CORPORATION 发明人 SULKOWSKI, THEODORE SYLVESTER;SILVER, PAUL JOSEPH;MASCITTI, ALBERT ANGELO
分类号 C07D471/04;(IPC1-7):C07D471/04;A61K31/435 主分类号 C07D471/04
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