发明名称 4(5)-SUBSTITUTED IMIDAZOLES
摘要 This invention provides imidazole derivatives of the formula <CHEM> wherein Q is hydrogen or hydroxy and R1 and R2 are independently F or Cl, or a pharmaceutically acceptable salt thereof. alpha , alpha -Bis(4-chlorophenyl)-1H-imidazole-4(5)-methanol, or a pharmaceutically acceptable salt thereof, and their pharmaceutical formulations which are useful in inhibiting aromatase or treating or preventing estrogen-dependent diseases in mammals.
申请公布号 ZA8504400(B) 申请公布日期 1987.02.25
申请号 ZA19850004400 申请日期 1985.06.11
申请人 ELI LILLY AND COMPANY 发明人 KENNETH STEVEN HIRSCH;HAROLD MELLON TAYLOR
分类号 C07D231/12;A61K31/415;A61K31/4164;A61P35/00;A61P43/00;C07D233/54;C07D233/64 主分类号 C07D231/12
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