摘要 |
Para-substd. 3-phenoxy-1-piperidine carbonylaminoalkylamino -propanol cpds. of formula (I) and their salts are new. (R1=H or an acyl gp. CO(O)pR4; p=0 or 1; R4=an aliphatic, cycloaliphatic or aromatic gp. opt. substd. and/or interrupted by heteroatoms; Ar=an aromatic or heteroaromatic gp., pref. of formula (II) m=0 or 1; n=1-3 provided that n=2-3 when m=1; R2=OR3, O-(CH2)qO-R3, a pyrazole gp. or NHCONHR3; q=2-3; R3=1-8C alkyl or 4-8C cycloalkylalkyl; X=N or C-R; R=H, CN or OCH3). |