发明名称 NEW PARA-SUBSTITUTED 3-PHENOXY-1-PIPERIDINECARBONYLAMINOALKYLAMINO-PROPANOL-2-S HAVING BETA RECEPTOR BLOCKING PROPERTIES
摘要 Para-substd. 3-phenoxy-1-piperidine carbonylaminoalkylamino -propanol cpds. of formula (I) and their salts are new. (R1=H or an acyl gp. CO(O)pR4; p=0 or 1; R4=an aliphatic, cycloaliphatic or aromatic gp. opt. substd. and/or interrupted by heteroatoms; Ar=an aromatic or heteroaromatic gp., pref. of formula (II) m=0 or 1; n=1-3 provided that n=2-3 when m=1; R2=OR3, O-(CH2)qO-R3, a pyrazole gp. or NHCONHR3; q=2-3; R3=1-8C alkyl or 4-8C cycloalkylalkyl; X=N or C-R; R=H, CN or OCH3).
申请公布号 ZA8604173(B) 申请公布日期 1987.02.25
申请号 ZA19860004173 申请日期 1986.06.04
申请人 AKTIEBOLAGET HAESSLE 发明人 TOMMY INGEMAR ABRAHAMSSON;BILL BENJAMIN RUDOLF GUSTAFSSON
分类号 C07D211/46;A61K31/44;A61K31/4427;A61K31/445;A61P9/08;A61P9/10;A61P9/12;A61P25/02;A61P27/02;A61P27/06;C07D;C07D211/00;C07D211/44;C07D211/98;C07D213/00;C07D231/00;C07D401/00;C07D401/12 主分类号 C07D211/46
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