发明名称 Derivatives of 2-fluoroalkylbenzimidazole, process for their preparation and pharmaceutical compositions containing them.
摘要 <p>A compound of the general formula 1: &lt;Chemistry id="chema01" num="0001"&gt;&lt;Image id="ia01" he="28" wi="85" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /&gt;&lt;/Chemistry&gt;or a salt or solvate thereof, in which, R' represents hydrogen or a lower alkyl group, R&lt;Sup&gt;2&lt;/Sup&gt; represents hydrogen, a lower alkyl group, or &lt;Chemistry id="chema02" num="0002"&gt;&lt;Image id="ia02" he="13" wi="30" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /&gt;&lt;/Chemistry&gt;R&lt;Sup&gt;3&lt;/Sup&gt; represents hydrogen, a lower alkyl group, or &lt;Chemistry id="chema03" num="0003"&gt;&lt;Image id="ia03" he="14" wi="44" file="IMGA0003.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /&gt;&lt;/Chemistry&gt;R&lt;Sup&gt;4&lt;/Sup&gt; represents a lower alkyl group substituted by one or more fluorine atoms, R&lt;Sup&gt;5&lt;/Sup&gt; represents hydrogen, halogen or lower alkyl, and</p><p>R&lt;Sup&gt;6&lt;/Sup&gt; represents a lower alkyl or a substituted or unsubstituted carbocyclic aryl group.</p>
申请公布号 EP0211489(A2) 申请公布日期 1987.02.25
申请号 EP19860304562 申请日期 1986.06.13
申请人 BEECHAM GROUP PLC 发明人 MARKWELL, ROGER EDWARD;SMITH, STEPHEN ALLAN
分类号 A61K31/415;A61K31/4184;A61P1/04;A61P11/00;A61P27/16;A61P29/00;A61P37/08;C07D235/10;(IPC1-7):C07D235/10 主分类号 A61K31/415
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