发明名称 |
EXPRESSION OF PLASMODIUM FALCIPARUM POLYPEPTIDES FROM CLONED CDNA |
摘要 |
DNA molecules comprising artificially constructed polynucleotide sequences substantially corresponding to all or a portion of Plasmodium falciparum messenger RNA (mRNA) or genomic DNA (gDNA). Especially DNA molecules comprising artificially constructed polynucleotide sequences coding for the whole or part of one or more proteins occuring in P. falciparum, or a precursor or modification thereof. Such DNA molecules are capable of being expressed as a polypeptide(s). Synthetic peptides or polypeptides displaying the antigenicity of all or a portion of at least one P. falciparum antigen. Compositions for stimulating immune responses against P. falciparum antigens in a mammal, comprising at least one polypeptide displaying the antigenicity of a P. falciparum antigen, together with a pharmaceutically acceptable carrier therefor. |
申请公布号 |
GB2143830(B) |
申请公布日期 |
1987.02.25 |
申请号 |
GB19840024104 |
申请日期 |
1984.01.27 |
申请人 |
THE * WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH |
发明人 |
DAVID JAMES * KEMP;ROBIN FREDRIC * ANDERS;ROSS LEON * COPPEL;GRAHAM VALLANCY * BROWN;ROBERT BRYCE * SAINT;ALAN FREDERIC * COWMAN;GRAHAM FRANK * MITCHELL |
分类号 |
A61K39/015;A61K39/00;A61P31/04;C07K14/00;C07K14/44;C07K14/445;C07K19/00;C12N1/21;C12N15/09;C12P21/02;C12R1/19;F02B75/02;(IPC1-7):C12N15/00;C07G17/00;C12P19/34;C12P21/00 |
主分类号 |
A61K39/015 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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