发明名称 |
Increasing labeling efficiency by forming diagnostic agent in the presence of ascorbic acid or the like |
摘要 |
A radioactive diagnostic agent having high labeling efficiency, prepared by bringing an aqueous solution of a radioactive metallic element contaminated with a non-radioactive metallic ions into contact with a non-radioactive carrier comprising a carrier substance having a chelate-forming property and optionally a physiologically active substance chemically bonded thereto, at least one of said aqueous solution and said non-radioactive carrier comprising at least one reductive material chosen from ascorbic acid and erythrobic acid, and their salts and esters.
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申请公布号 |
US4645660(A) |
申请公布日期 |
1987.02.24 |
申请号 |
US19840604261 |
申请日期 |
1984.04.26 |
申请人 |
NIHON MEDI-PHYSICS CO., LTD. |
发明人 |
TAKAHASHI, KEIETSU;UEDA, NOBUO;HAZUE, MASAAKI;YOKOYAMA, AKIRA;OHMOMO, YOSHIRO |
分类号 |
A61K51/00;A61K51/08;A61K51/12;(IPC1-7):A61K43/00;A61K49/00 |
主分类号 |
A61K51/00 |
代理机构 |
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代理人 |
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地址 |
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