| 发明名称 |
METHOD FOR PRODUCING HUMAN IMMUNE INTERFERON |
| 摘要 |
FIELD: medical engineering; biological engineering. SUBSTANCE: method involves designing recombinant plasmid pSVpSVgamma 69 having DNA fragment encoding predecessor of human immune interferon, transforming COS-7 cells line with the produced recombinant vector, selecting transformed cells that are cultured under conditions providing target product accumulation and selecting mature form of gamma-interferon possessing no N-terminal Cys-Tyr-Cys (des-Cys-Tyr-Cys)gamma- interferon. EFFECT: enhanced reliability of method. 8 dwgo |
| 申请公布号 |
RU2107728(C1) |
申请公布日期 |
1998.03.27 |
| 申请号 |
SU19884355606 |
申请日期 |
1988.04.28 |
| 申请人 |
GENENTEK INK. |
发明人 |
DEHVID V.GOEDDEL;PATRIK V.GREJ;DEHVID V.GOEDDEL;PATRIK V.GREJ |
| 分类号 |
C12N1/19;A61K35/14;A61K35/23;A61K38/00;A61K38/16;A61K38/21;A61P31/12;A61P35/00;A61P43/00;C07H21/04;C07K1/00;C07K1/22;C07K14/00;C07K14/52;C07K14/555;C07K14/57;C12N1/00;C12N1/21;C12N5/00;C12N5/10;C12N15/00;C12N15/09;C12N15/20;C12N15/23;C12N15/70;C12N15/71;C12N15/81;C12N15/85;C12P21/02;C12R1/045;C12R1/19;C12R1/865;C12R1/91 |
主分类号 |
C12N1/19 |
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