发明名称 Isatoic and aza-isatoic acid anhydride(s) prepn. - by alkali treatment of halo-imide(s) of aromatic di:carboxylic acids and acidification
摘要 <p>The anhydrides of isatoic acid and 3-aza isatoic acid, for use in making pharmaceutical and agricultural prods., and perfumery essences, are made by (a) reacting an imide of formula (I) in which X is Br or Cl and Z is N or CH, in aq. medium contg. 1.5-3 equivs. alkali or alkaline earth hydroxide per equiv. imide at around 0 deg.C with slow stirring; (b) cooling for sufficient time to achieve pH 5.5-7; (c) heating to 30-45 deg.C with an exothermic reaction, keeping at pH 5.5 min. until complete, and (d) filtering off, washing and drying the anhydride crystals.</p>
申请公布号 ES8700854(A3) 申请公布日期 1987.02.01
申请号 ES19550005475 申请日期 1985.10.03
申请人 GEN QUIMICA S A 发明人
分类号 C07D265/26;C07D498/04;(IPC1-7):C07D265/26 主分类号 C07D265/26
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