发明名称 2-ARYL NAPHTHALENE DERIVATIVES
摘要 The compounds in question correspond to the following general formula: <IMAGE> in which: X represents -CH=CH-, O or S, R1 and R2, which may be identical or different, represent a hydrogen atom, a linear or branched alkyl radical having from 1 to 15 carbon atoms or an alkoxy radical having from 1 to 6 carbon atoms, or R1 and R2, taken together and with the adjacent carbon atoms of the naphthalene ring-system, form a 5- or 6-membered ring optionally substituted with at least one lower alkyl radical or interrupted by an oxygen atom, and R3 represents a -CH2OH radical or a radical -COR4, or alternatively a -CH3 radical in the case where R1 and R2, taken together form a 5- or 6-membered ring, R4 representing -OR5 or <IMAGE> R5 representing a hydrogen atom, an alkyl radical having 1 to 20 carbon atoms, monohydroxyalkyl, polyhydroxyalkyl, aryl or aralkyl radical, optionally substituted, or a sugar residue, or alternatively represents a radical: <IMAGE> p being 1, 2 or 3, r' and r'' representing a hydrogen atom, a lower alkyl radical, a monohydroxyalkyl or polyhydroxyalkyl radical, an optionally substituted aryl radical or an amino acid residue or amino sugar residue, or alternatively, taken together, form a heterocycle, including the salts of the derivatives of formula (I).
申请公布号 AU6049986(A) 申请公布日期 1987.01.29
申请号 AU19860060499 申请日期 1986.07.24
申请人 CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. 发明人 BRAHAM SHROOT;JACQUES EUSTACHE;OLIVER WATTS;JEAN-MICHEL BERNARDON;PHILIPPE NEDONCELLE
分类号 C07C43/23;A61K8/00;A61K8/30;A61K8/34;A61K8/36;A61K8/368;A61K8/37;A61K8/41;A61K8/42;A61K8/49;A61K31/045;A61K31/165;A61K31/19;A61K31/215;A61K31/235;A61K31/34;A61K31/341;A61K31/357;A61K31/38;A61K31/381;A61P17/00;A61P27/02;A61P43/00;A61Q5/02;C07C27/00;C07C29/147;C07C33/18;C07C33/34;C07C41/30;C07C43/303;C07C45/00;C07C47/52;C07C51/00;C07C63/331;C07C63/49;C07C65/24;C07C65/26;C07C67/00;C07C69/76;C07C69/94;C07C233/65;C07C233/68;C07C235/42;C07D307/42;C07D307/68;C07D311/92;C07D319/06;C07D333/38;C07H13/08;C07H13/10 主分类号 C07C43/23
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