| 发明名称 |
DIBENZO[A,G]QUINOLIZINIUM DERIVATIVES AND THE SALTS THEREOF |
| 摘要 |
The present invention provides a 5,6-dihydrodibenzo[a,g]quinolizinium derivative and the salts thereof of formula (I) which specifically inhibits the sterol 14-reductase which is involved in the distal pathway of cholester ol biosynthesis, and the use of the compound of formula (I) for treating hypercholesterolaemia or hyperlipidaemia, wherein R1, R2, R3, R4, X and 2 ar e defined in the claims.
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| 申请公布号 |
CA2355469(A1) |
申请公布日期 |
2000.06.29 |
| 申请号 |
CA19992355469 |
申请日期 |
1999.01.19 |
| 申请人 |
HANWHA CHEMICAL CORPORATION |
发明人 |
LEE, YOU, SUK;KIM, SEUNG UN;KIM, EUI DEOK;PARK, JOON SEO;JHONG, TAE NEUNG;PAIK, YOUNG KI;KIM, JUNG HO |
| 分类号 |
C07D455/03;A61K31/00;A61K31/435;A61K31/4353;A61K31/4375;A61K31/47;A61P3/00;A61P3/06;A61P43/00;C07D471/04;C07D491/056;C07D491/147;(IPC1-7):C07D471/04 |
主分类号 |
C07D455/03 |
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