摘要 |
The invention provides a method of combating a microorganism which comprises allowing a heterocyclic pentalene derivative of general formula I <IMAGE> (I) wherein X represents an oxygen atom, a sulphur atom or an -SO- moiety; Y represents a sulphur, selenium or tellurium atom, provided that when Y represents a selenium or tellurium atom X is an oxygen atom; and R1 and R2 together represent a -CH2-C(CH3)2-CCl(CONH2)- or -CH2-A-CH2- linkage where A is a -CH2-, -CH(CH3)- or -S(O)n- moiety, where n is 0, 1 or 2; provided that when X is an oxygen atom and Y is a sulphur atom R1 and R2 together represent a -CH2-S(O)n-CH2- linkage and when X is an -SO- moiety and A is a S(O)n-, n is 2; to act on the microorganism or its environment; and such derivatives for use as a therapeutic substance. |