发明名称 PENTAPEPTIDES WITH CELL GROWTH REGULATORY EFFECTS AND A PROCESS FOR THE PREPARATION THEREOF
摘要 New pentapeptide of formula (I), in which X<1> and X<2> are the same or different and are OH or NH2, Y is H or OH, X<3> is CO or CH2, one of the groups Z<1> and Z<2> is H and the other is H or CH3, all the amino acid units being in L-configuration, with the exception that the C-terminal amino acid unit is in D-configuration when Z<2> is methyl, and the C-terminal carboxyl group may be reduced to -CH2-OH or be in amide form, and cation complexes and salts thereof. The pentapeptide may be prepared by subjecting a protected derivative thereof to deprotection. The pentapeptide has cell growth regulatory activity.
申请公布号 WO8700180(A1) 申请公布日期 1987.01.15
申请号 WO1986NO00041 申请日期 1986.06.18
申请人 BIOTECH AS 发明人 ELGJO, KJELL;REICHELT, KARL-LUDVIG
分类号 C07K5/10;A61K38/00;A61P17/00;A61P43/00;C07K1/04;C07K1/06;C07K7/06;(IPC1-7):C07K7/06 主分类号 C07K5/10
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