Diamino-androstane derivatives.

摘要

The invention relates to new 6, 16-diamino-androstane derviatives of formula (I) <CHEM> wherein Y is hydrogen or an OAc group, Ac is an alkylcarbonyl group having from 1 to 4 carbon atoms in the alkyl moiety, A is methylene or a group of formula N-R<1> (wherein R<1> is alkyl having from 1 to 4 carbon atoms). B is methylene, or a group N-R<1> or N-R<2>, in which R<1> is as defined above and R<2> is a -CH2-CH2-COOR<1>, and n is 1 or 2, m is 1, 2 or 3, and physiologically acceptable diquaternary and monoquaternary salts thereof with C1-4 alkyl or alkenyl groups. Processes for preparing the compounds of formula (I) and compositions containing them are also disclosed. The compounds are potentially valuable as muscle relaxants.