The present invention provides a nucleic acid sequencing method. The method comprises enriching a nucleic acid sample for target nucleic acids, where the nucleic acid sample is enriched through at least a first round of hybridization selection and amplification, and a second round of hybridization selection and amplification. The enriched nucleic acids are in a form convenient for sequencing with the Cantaloupe sequencing technology, which employs shotgun sequencing by hybridization (SBH) of immobilized rolling circle amplicons.
申请公布号
WO2007106509(A2)
申请公布日期
2007.09.20
申请号
WO2007US06372
申请日期
2007.03.14
申请人
GENIZON BIOSCIENCES, INC.;BELOUCHI, ABDELMAJID;GEOFFROY, STEVE;LINNARSSON, STEN;BERUBE, PIERRE;KEITH, TIM
发明人
BELOUCHI, ABDELMAJID;GEOFFROY, STEVE;LINNARSSON, STEN;BERUBE, PIERRE;KEITH, TIM