发明名称 Antihypertensive 3-(ureidocyclohexyleneamino)propane-1,2-diol derivatives
摘要 Certain 3-(ureidocyclohexyleneamino)propane-1,2-diol derivatives, such as the compounds of formula III below, represent novel and useful pharmaceutical agents, e.g. potent antihypertensive and cardioactive agents demonstrating both alpha - and beta -adrenergic blocking activity. <IMAGE> (III) R3 is hydrogen or lower alkyl; R7 is cyano, lower alkoxycarbonyl, pyrrolyl, morpholino, alkenyloxy of 3 to 6 carbon atoms, alkynyloxy of 3 to 6 carbon atoms, alkoxy of 1 to 3 carbon atoms substituted by cyclopropyl.
申请公布号 US4634713(A) 申请公布日期 1987.01.06
申请号 US19850767232 申请日期 1985.08.19
申请人 CIBA-GEIGY CORPORATION 发明人 WERNER, LINCOLN H.;FORD, NEVILLE
分类号 A61K31/415;C07C43/23;C07C275/26;C07C275/40;C07D233/32;C07D233/34;C07D233/36;C07D303/24;C07D401/12;C07D403/12;C07D417/12;(IPC1-7):A61K31/415 主分类号 A61K31/415
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