| 摘要 |
PURPOSE:To obtain in high purity the titled substance useful as an intermediate for agricultural chemicals, drugs, etc., by using optically active 2-propargyl-4- hydroxy-2-cyclopentenone, a novel compound, as a raw material and hydrogenating it catalytically in the presence of a catalyst so that it is partially reduced. CONSTITUTION:2-Propargyl-4-hydroxy-2-cyclopentenone, a novel compound, as a raw material is catalytically hydrogenated in the presence of a palladium catalyst in a solvent such as water, methanol, toluene, etc. usually at -20 deg.C-100 deg.C and partially reduced to give the titled compound. A Lindlar catalyst is especially preferable as the palladium catalyst and the amount of it used is 0.01-10wt% based on the raw material. The novel compound of the raw material, for example, is obtained by hydrolyzing asymmetrically dl-2- propargyl-4-acetoxy-2-cyclopentenone with esterase. |
