发明名称 |
NEUTROKINE-ALPHA AND NEUTROKINE-ALPHA SPLICE VARIANT |
摘要 |
The present invention relates to nucleic acid molecules encoding Neutrokine-alpha and/or Neutrokine-alphaSV polypeptides, including soluble forms of the extracellular domain. Neutrokine-alpha and/or Neutrokine-alphaSV polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to antibodies or portions thereof that specifically bind Neutrokine-alpha and/or Neutrokine-alphaSV and diagnostic and therapeutic methods using these antibodies. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating immune system-related disorders using the compositions of the invention. |
申请公布号 |
US2009104189(A1) |
申请公布日期 |
2009.04.23 |
申请号 |
US20080210134 |
申请日期 |
2008.09.12 |
申请人 |
HUMAN GENOME SCIENCES, INC. |
发明人 |
YU GUO-LIANG;EBNER REINHARD;NI JIAN;ROSEN CRAIG A.;ULLRICH STEPHEN |
分类号 |
A61K39/395;A61K31/519;A61K38/00;A61K39/00;A61K47/48;A61K49/00;A61P35/00;C07K14/52;C07K14/705;C07K14/715;C07K16/24;C07K16/28;C12Q1/00;G01N33/536;G01N33/564 |
主分类号 |
A61K39/395 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|