| 摘要 |
A method of treatment of migraine, cluster headaches and trigeminal neuralgia, radiation or cytotoxic agent induced nausea and vomiting and/or cardiac arrhythmia in mammals, including humans, which method comprises administering an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof: <IMAGE> (I) wherein: R1 is C1-6 alkyl; R2 is amino or C1-7 acylamino; R3 is halo; one of R4 and R5 is hydrogen, C1-6 alkyl, phenyl or phenyl C1-3 alkyl, which phenyl moieties may be substituted by one or more substituents selected from C1-6 alkyl, C1-6 alkoxy, CF3 or halogen; the other of R4 and R5 is hydrogen or C1-6 alkyl; p is 0 to 2; and q is 0 to 3. |
