发明名称 Substituted phenylpiperazinyl-propanols, a process for their preparation and their use, and formulations containing these compounds
摘要 Substituted phenylpiperazinyl-propanols of the formula I <IMAGE> (I) in which R1 denotes hydrogen or an alkyl group with 1 to 4 carbon atoms and R2 and R3, which can be identical or different, each denote hydrogen, halogen, cyano, a trifluoromethyl group, a nitro group, a hydroxyl group, an alkoxy group or an alkyl group with in each case 1 to 4 carbon atoms, it being possible for the alkyl parts in each case to be straight-chain or branched, and their tautomeric forms and their salts as well as acid addition salts and N-oxides, have useful pharmacological properties, in particular a positively inotropic, vasodilating, broncholytic and platelet aggregation-inhibiting action and are therefore suitable for the treatment of cardiac insufficiency, hypertension, asthma and thrombosis.
申请公布号 US4631281(A) 申请公布日期 1986.12.23
申请号 US19850750729 申请日期 1985.06.28
申请人 BEIERSDORF AKTIENGESELLSCHAFT 发明人 STENZEL, WOLFGANG;HOFFERBER, EVA
分类号 C07D295/08;A61K31/44;A61K31/4418;A61K31/495;A61P9/04;A61P9/12;C07D213/85;C07D303/22;(IPC1-7):A61K31/445;C07D401/10 主分类号 C07D295/08
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