| 摘要 |
NEW MATERIAL:The compound of formula I [the ring A is group of formula IIor formula III; R1 is lower alkyl; R2 is carboxyl, alkenyloxycarbonyl, (N,N-di- lower alkylamino, piperidino, or phenyl-substituted) lower alkoxycarbonyl or lower alkenyl having carboxyl or phenyl-lower alkoxycarbonyl, or lower alkyl having carboxyl or lower alkoxycarbonyl]. EXAMPLE:5,8-Dimethoxy-1,4-naphthoquinone-6-carboxylic acid. USE:Anti-inflammatory, cardiotonic, anti-allergic, antithrombotic, hypotensor, etc. PREPARATION:The compound of formula I wherein R2 is R3 except for formyl can be prepared by oxidizing the compound of formula IV (R3 is formyl, carboxyl, carboxy-lower alkenyl or lower alkyl, and a novel substance other than formyl) preferably with Jones reagent. |
