发明名称 UN PROCEDIMIENTO PARA PREPARAR D, L-(TREO) 1 ARIL-2-ACILAMIDO-3-FLUOR-1-PROPANOL.
摘要 <p>A novel sequence of highly selective chemical reactions for conversion of 3-Aryl-2-propyn-1-ols into cis-1-Aryl-3-fluoro-1-propene and into D,L-(threo)-1-Aryl-2-acylamido-3-fluoro-1-propanols is disclosed. Preparation of D-(threo)-1-Aryl-2-acylamido-3-fluoro-1-propanol antibacterial agents including the D-(threo)-3-fluoro-3-deoxy derivatives of chloramphenicol and thiamphenicol is also disclosed.</p>
申请公布号 ES547083(D0) 申请公布日期 1986.12.16
申请号 ES19830005470 申请日期 1985.09.18
申请人 SCHERING CORPORATION 发明人
分类号 C07D303/00;C07C231/16;C07C233/18;C07C247/04;C07C255/60;C07C311/15;C07C311/46;C07C311/47;C07C317/32;C07C317/44;C07D209/48;C07D301/14;C07D303/08;C07D303/34;(IPC1-7):C07C101/16;A61K31/23 主分类号 C07D303/00
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