发明名称 SLOW-RELEASING MEDICINAL PREPARATION FOR ORAL ADMINISTRATION
摘要 PURPOSE:To provide the titled preparation having minute granular to tablet form, containing a cellulose lower alkyl ether, polyacrylic acid or its pharmacologically permissible salt and a drug component and capable of slowly releasing the drug component in the stomach or intestiness by oral administration. CONSTITUTION:The titled preparation contains (A) a cellulose lower alkyl ether (e.g. hydroxypropyl cellulose), (B) a polyacrylic acid or its pharmacologically permissible salt and (C) a drug component. The form of the preparation is preferably small granule having particle diameter of 0.5-2mm or a tablet of 2-8mm in diameter and 1-5mm in thickness. The weight ratio A:B is 10:(0.1-10). The component B is homopolymer or copolymer of acrylic acid. The rate of release of the drug component can be controlled to meet the remedying purpose by changing the ratio of A to B.
申请公布号 JPS61286330(A) 申请公布日期 1986.12.16
申请号 JP19850125139 申请日期 1985.06.11
申请人 TEIJIN LTD 发明人 IGURA HIROSHI;SUZUKI YOSHIKI;NAGAI TSUNEJI;MACHIDA RYOJI
分类号 A61K47/38;A61K9/16;A61K9/22;A61K47/00;A61K47/32 主分类号 A61K47/38
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