| 摘要 |
NEW MATERIAL:A compound expressed by formula I (Y is =CH- or N; R is lower alkyl). EXAMPLE:7beta-[ 2-(2-Aminothiazol-4-yl)-2-(Z)-methoxyiminoacetamido]-3-(1,5-trime thylene-2-pyrazolio)methyl-3-cephem-4-carboxylate. USE:An antimicrobial agent against Gram-positive and Gram-negative bacteria. PREPARATION:A compound expressed by by formula III, a compound having the protected functional groups or a salt thereof, e.g. 7beta-[2-(2-aminothiazol-4- yl)-2-( Z )-methoxyiminoacetamido]-3-acetoxymethyl-3-cephem-4-carboxylic acid, is reacted with 1,5-trimethylenepyrazole expressed by formula IV. |
