发明名称 Indolinones and pharmaceutical compositions containing same
摘要 The present invention relates to novel indolinones of the general formula <IMAGE> wherein R represents an aryl group having from 6 to 10 carbon atoms, unsubstituted or mono- or disubstituted by alkyl groups having from 1 to 5 carbon atoms, hydroxyl groups, alkoxy groups having from 1 to 3 carbon atoms, or halogen atoms, whereby the substituents may be the same or different and whereby the phenyl nucleus of the aryl group may also be substituted by an amino group, a hydroxyl group, or an alkanoylamino group with altogether from 1 to 3 carbon atoms; an aryl group having from 6 to 10 carbon atoms, substituted by 3 or 4 alkyl groups having from 1 to 5 carbon atoms each; a phenyl group substituted by a phenyl, halogenphenyl, or cycloalkyl group with 5 to 7 carbon atoms; an aralkyl group having from 7 to 11 carbon atoms; or a pentamethylphenyl, pyridyl, or quinolyl group; m represents the number 0, 1, or 2; and n represents the number 2, 3, 4, 5, or 6.
申请公布号 US4629733(A) 申请公布日期 1986.12.16
申请号 US19840625020 申请日期 1984.07.27
申请人 DR. KARL THOMAE GMBH 发明人 MUELLER, ERICH;NICKL, JOSEF;ROCH, JOSEF;NARR, BERTHOLD;HAARMANN, WALTER;WEISENBERGER, JOHANNES M.
分类号 C07D209/12;A61K31/40;A61K31/403;A61K31/404;A61K31/44;A61K31/4427;A61P7/02;C07D209/34;C07D401/12;(IPC1-7):A61K31/40 主分类号 C07D209/12
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