| 摘要 |
NEW MATERIAL:A cis-diaminocyclohexanolplatinum comples expressed by formula I, II, III or IV (R<1>-R<8> are H or OH, provided that one carbon atom is not substituted by two OH groups in the carbon atoms constituting the cyclohexane ring). EXAMPLE:Dichloro(2-deoxystreptamine)platinum (II). USE:An antitumor agent having improved antitumor activity equal to or better than that of cisplatin and readily administrable due to high solubility thereof. PREPARATION:An aqueous solution of diaminocyclohexanol hydrochloride or hydrobromide which is a starting material is added to an aqueous solution of potassium chloroplatinate (II) which a starting material to carry out reaction and soldium hydrogencarbonate is added thereto. the resultant mixture is allowed to stand in a refrigerator to deposit crystals of the aimed compound.
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