| 摘要 |
<p>A DNA sequence which is deleted in a number of Duchenne Muscular Dystrophy (DMD) patients has been located. The sequence hybridises strongly to mRNA from human fetal muscle but only weakly to mRNA from human or rat adult muscle. It does not hybridise to mRNA derived from human fetal fibroblasts. The DNA sequence or a portion thereof can be used as a hybridisation probe in screening X-chromosomal DNA from patients to detect the presence of mutational DMD sites.</p> |
