| 摘要 |
<p>Trisazolo¢2,3-c!¢1,3!benzodiazepines The invention concerns 5-diazacycloalkyl-1,2,4-triazolo¢2,3-c!-¢1,3!benzodiazepines of formula I (I) < IMG > wherein R1 is hydrogen, lower alkylthio, amino, (acyl, mono- or di-lower alkyl)-amino, lower alkoxy, acyloxy, lower alkyl, lower alkanoyl, hydroxy, halogen, trifluoromethyl, cyano, carboxy, lower alkoxycarbonyl, carbamoyl, mono- or di-lower alkyl-carbamoyl, hydroxy-lower alkyl or di-lower alkylamino-lower alkyl; CnH2n is lower alkylene separating both nitrogen atoms by 2 or 3 carbon atoms; R2 is hydrogen, lower alkyl, lower alkenyl, lower alkynyl, lower alkanoyl, aryl-lower alkyl, lower alkoxycarbonyl, phenyl lower alkoxycarbonyl or (hydroxy, lower alkanoyloxy, aryloxy or lower alkoxy)-lower alkyl having at least two carbon atoms; R3 and R4 independently represent hydrogen, lower alkyl, lower alkoxy, lower alkylthio, halogen, trifluoromethyl, hydroxy, lower alkanoyloxy, sulfamoyl, mono- or di-lower alkylsulfamoyl; and R5 and R6 represent hydrogen or lower alkyl; the N-oxides; and salts.</p> |
