Absorbent of autoantibody and immune complexes, adsorbing device and blood purifying apparatus comprising the same

摘要

An adsorbent for adsorbing thereonto an autoantibody and/or immune complexes from a body fluid. The adsorbent comprises a surface, a hydrophobic member and a negative charge-producing member. The negative charge-producing member is adapted to produce such an effective number of negative charges in a body fluid that the ratio of: <IMAGE> is greater than 1. The adsorbent is excellent in selectively and efficiently adsorbing an autoantibody and/or immune complexes while little adsorbing useful substances from the body fluid. The adsorbent may be used in an adsorbing device comprising a vessel having a fluid inlet and a fluid outlet with the adsorbent contained in the vessel. The adsorbing device may be used in a blood purifying apparatus for adsorbing and removing an autoantibody and/or immune complexes from blood plasma, which apparatus comprises a blood circulation passage provided with a plasma separating means and a blood-plasma mixing means, and a plasma recycle passage connected to the blood circulation passage and adapted to introduce plasma, separated by the plasma separating means and purified by a plasma purifying means comprised of the above-mentioned adsorbing device and disposed in the plasma recycle passage, into the mixing device.