MONOCLONAL ANTIBODIES REACTIVE WITH SHARED IDIOTYPES ON HUMAN ANTIBODIES TO NATIVE DNA FROM PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS

摘要

Title MONOCLONAL ANTIBODIES REACTIVE WITH SHARED IDIOTYPES ON HUMAN ANTIBODIES TO NATIVE DNA FROM PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS The invention relates to monoclonal anti-idio-typic antibodies to human anti-DNA antibodies. Monoclonal, anti-idiotypic antibodies are produced using hybridoma technology. The antibodies ate used as diagnostic reagents in methods to determine the presence of anti-native DNA antibodies in serum from patients suspected of having systemic lupus erythema tosus.