发明名称 Spiro-imidazolidines as aldose reductase inhibitors.
摘要 <p>Spiro-imidazolidines of the formula: &lt;CHEM&gt; and the pharmaceutically acceptable salts thereof, wherein X is O, CH2 or NH; R is hydrogen, fluoro, chloro, methyl or methoxy; and Y is O or CH2. &lt;??&gt;These compounds are useful in treatment to prevent or alleviate ocular or neuritic diabetes-associated chronic complications. </p>
申请公布号 EP0203791(A1) 申请公布日期 1986.12.03
申请号 EP19860303925 申请日期 1986.05.23
申请人 PFIZER INC. 发明人 LIPINSKI, CHRISTOPHER ANDREW
分类号 A61K31/415;A61K31/4184;A61K31/47;A61P3/08;A61P3/10;A61P27/02;A61P27/12;C07D233/78;C07D235/02;C07D471/10;C07D491/052;C07D491/10;C07D491/107;(IPC1-7):C07D235/02 主分类号 A61K31/415
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