发明名称 Tetra:hydro indole acetic acid deriv. prepn.
摘要 <p>Method comprises (a) reacting 7-ethyl triptophal with a 3-oxopentanioc acid ester and a low mol wt. alcohol e.g. methyl alcohol in toluene, in presence of p-toluenesulphonic acid under reflux for 8-24 hrs. to give an ester and (b) hydralysing in basic medium to give a tetrahydro (3,4-b) indole acetic acid deriv. (I). Prod. (I) is 1,8-diethyl-1,3,4,9-tetra-hydropiran (3,4-b) indole acetic acid.</p>
申请公布号 ES8608521(A1) 申请公布日期 1986.12.01
申请号 ES19410005416 申请日期 1985.03.27
申请人 LABORATORIO FARMACEUTICO QUIMICO LAFARQUIM, S.A. 发明人
分类号 A61K31/35;A61K31/405;C07D491/052;(IPC1-7):C07D491/052 主分类号 A61K31/35
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