SUBTILISINHALTIG PROTEASPRODUKT MED REDUCERAD ALLERGENICITET HERLEDD UR BACILLUS LICHENIFORMIS, FORFARANDE FOR DESS FRAMSTELLNING, TVETTMEDELSKOMPOSITION INNEHALLANDE DENSAMMA SAMT B. LICHENIFORMISSTAM NRRL B-11301, B-1

摘要

A novel protease product suitable for admixture to washing compositions and exhibiting substantially attenuated allergenic properties is prepared by cultivating strains of Bacillus licheniformis which have been mutated to block their synthesis of protease other than Subtilopeptidase A (subtilisin). The commercial Bacillus licheniformis derived protease products are mixtures of subtilisin and a non-serine protease of lower stability and greater allergenicity than subtilisin.