NOVEL AMINOGLYCOSIDE DERIVATIVE

摘要

NEW MATERIAL:A compound shown by the formula I (R<1> is higher alkanoylamino; R<2> is amino which may be protected; X<1>-X<3> are amino or acylamino). EXAMPLE:1-N-Parmitoyl-3''-trifluoroacetyltobramycin. USE:A preventive and remedy for infectious diseases of pathogenic microorganisms. PREPARATION:A compound shown by the formula II or a reactive derivative at the amino group or its salt is acylated, or a compound shown by the formula III (Xa<1>, Xa<2> and Xa<3> are acylamino) or its salt is deacylated.