发明名称 CARCINOSTATIC ADJUVANT
摘要 PURPOSE:A carcinostatic adjuvant, consisting of an extract of decoction of ephedra herb and useful for cisplatin. CONSTITUTION:A carcinostatic adjuvant obtained by adding an extraction solvent, e.g. water or water-soluble organic solvent, in an amount of 5-25 times, preferably 8-20 times, based on ephedral herb decoction, to the ephedral herb decoction (3.0-5.0pts.wt. ephedral herb, 4.0-5.0pts.wt. apricot kernel, 2.0-4.0pts.wt. cinnamon bark and 1.0-2.0pts.wt. licorice), extracting the ephedral herb decoction at 60-100 deg.C for 30min-2hr while heating, filtering the above- mentioned extract, concentrating the filtrate by a means of vacuum concentration, etc., and drying the concentrate by a drying means and capable of enhancing the carcinostatic action of cisplatin and reducing side effect. The cisplatin is a carcinostatic agent effective for testicular tumor, prostatic carcinoma, bladder cancer, ovarian cancer and renal pelvis and urethrophyma, but has side effect, e.g. renopathy, etc. The above-mentioned side effect is reduced by the above-mentioned adjuvant and, therefore, the treatment of cancer by the cisplatin becomes more effective.
申请公布号 JPS61263925(A) 申请公布日期 1986.11.21
申请号 JP19850107685 申请日期 1985.05.20
申请人 KANEBO LTD 发明人 KINOSHITA MASAHIKO;IKEDA YOSHIAKI;TAKEBE HIDETARO;SAITO YUJI
分类号 A61K33/24;A61K36/00;A61P35/00 主分类号 A61K33/24
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