| 摘要 |
NEW MATERIAL:The ascorbic acid derivative of formula I (R<1> is organic residue having a molecular weight of 15-700; R<2> is H or OH; R<3> is H, acyl, phosphono or sulfo group; R<3> may together with OH of R<2> form an acetal residue or ketal residue; when R<2> is OH and R<3> is H, R<1> is a group other than organic residue having a molecular weight of 15-400 except for a 1-22C alkyl substituted with benzyl, phenacyl, cycloalkylmethyl, OH or benzyloxy which has substitutent group) or its salt. EXAMPLE:2-0-(8-Benzyloxyoctyl)-L-ascorbic acid. USE:Preventive and remedy for circulatory system disorder. PREPARATION:For example, the compound of formula I can be produced either by hydrolyzing the compound of formula II (R<4> is a group eliminable by hydrolysis or reduction; X is two H atoms, or an acetal residue or ketal residue) or hydrolyzing and then reducing the compound of formula II.
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