| 摘要 |
A polymeric diffusion matrix for administering a drug is provided comprising from about 2 to about 60% of a polar plasticizer, e.g., glycerol, from about6 to about 20% of polyvinylalcohol, from about 2 to about 10% of polyvinylpyrrolidone, and a pharmaceutically effective amount of drug, yielding a matrix capable of sustained release of a vasodilator drug dispersed therein, and the balance water, the percentages being by weight. The drugs include terbutaline, ephedrine, clonidine, phenylephrine, estradiol esters, phenylpropanolamine, and chlorpheniramine maleate. |
